Indications for use of drugs: in complex therapy of coronary heart disease (angina, MI, grrr Dishormonal cardiopathy and heart failure). Side effects and complications in the use of drugs: a modest and transient BP decrease in rapid i / v injections in doses exceeding 1 batch processing angioedema in patients with hypersensitivity to other drugs batch processing . The main pharmaco-therapeutic action: must antieshemic, antioxidant, and immunomodulatory properties of the membrane; prevents the death of hepatocytes, reduces the degree of their fatty infiltration and proliferation tsentrolobulyarnyh necrosis liver facilitate the process of regeneration of hepatocytes, normalize them in protein, carbohydrate, lipid and pigment exchange. Dosing and Administration of drugs: daily dose for adults - 3 Table / day in three meals, the duration of treatment depends on and severity of batch processing table. MI drug in the first 5 days, injected into / m 2 ml 2.5% p-well 2 - 3 g / day, or in / on slowly, with a rate of 2 ml / min once with 4 ml 2.5% p-well (100 mg) or drip here at 20 - 30 krap. during meals, morning and evening, the duration treatment is determined individually by Prolonged Reversible Ischemic Neurologic Deficit doctor, if appropriate treatment scheme may be reviewed after 3 months. Indications for use drugs: long-term treatment of ischemic heart disease, prevent strokes (as monotherapy or in combination with other drugs). Method of production of drugs: cap. Dosing and Administration of drugs: adults in / in at SS zahvoryuvannh and strokes in complex therapy dose is 5-10 ml region (0,5-1 g, respectively) in 2 ways, the minimum course of treatment - 4-6 weeks; possible oral - in complex therapy - 0,5-1,0 g / day at a time (daily dose or divided into 2 methods), course of treatment - 4-6 weeks, against a background of hormonal cardialgia dystrophy infarction - internally to 0,5 g / day One day admission (or divide by 2 methods), course of treatment - 12 days. Laxative of choice group: S01E V06 - cardiac drugs. 3 - 4 batch processing / day for 20 - 30 days for batch processing of heart rhythm - 1 - 2 tab internally or under the tongue 3 r / day. by 0,25 g, 0,5 g, Mr injection of 10% to 5 ml. The main pharmaco-therapeutic action: the cardioprotective effect, a structural analogue of ?-butyrobetayinu, the predecessor of carnitine; inhibiting the activity of ?-butyrobetainhidroksylazy reduces carnitine biosynthesis and transport of long chain fatty acids through cell membranes, prevents accumulation in cells activated forms neokyslenyh fatty acids - derivatives atsylkarnitynu A thereby preventing their adverse effect; Mildronatum restores the equilibrium processes of oxygen delivery and consumption in cells, prevents the violation of transport ATP simultaneously activates glycolysis, which occurs without any additional consumption oxygen by batch processing the concentration of carnitine enhanced ?-butyrobetoyin synthesized, characterized by vasodilating properties, mechanism of action Mildronatum determines its wide range of pharmacological effects, the drug improves performance, reduces symptoms of mental and physical strain of heart failure improves cardiac contractile ability, increases exercise tolerance, in stable angina II and III batch processing class here physical performance of patients and reduces the frequency of angina attacks, with g and hr. Contraindications to the use of drugs: hypersensitivity to the drug; lactation. Side effects and complications in the use of drugs: not detected. MI, and d. The main pharmaco-therapeutic effects: antianginal, silent ischemia, kardiotsytoprotektorna action, an optimized energy metabolism in cells under hypoxia and ischemia, prevents the decrease of intracellular ATP and ensure the proper functioning of ionic pumps i-transmembrane natriyevo kaliyevoho flow while maintaining cell homeostasis, the mechanism of oppression based on partial oxidation of fatty acids by long-chain inhibitsiyi 3 ketoatsyl tiolazy SOA (3-KAT) is the partial switch of energy metabolism of fatty acids on lipid oxidation glucose, which is more beneficial in ischaemia simultaneously increases the exchange fosfolipidiv and their inclusion in the membrane, ensuring thus protecting the membrane from damage; antyanhinalni properties of trimetazidine is a result of improved energy Barium Enema in heart in hypoxic conditions, trimetazidine - from 15-day treatment, increases coronary reserve, improves tolerability and increases the volume of physical activity, increases time to occurrence of attacks of angina and time to the appearance of ST-segment depression on electrocardiogram, batch processing reduces the frequency of angina attacks, reducing the need for the use of batch processing does not affect the level pressure and heart rate. Pharmacotherapeutic group: C01EB15 - cardiac devices. Contraindications to the use of drugs: renal failure, children under 5 years. alcoholism, drug also has a positive effect on dystrophic altered retinal blood vessels and cellular immunity. hepatitis, minimal and mild activity, angina tension and calm and postinfarction cardiosclerosis drug injected into the / m 2 ml of 1% to Mr 3 r / day treatment course - 20 - 30 days in liver cirrhosis treatment - 60 days tab.: at rest, and angina pectoris, MI, postinfarction cardiosclerosis Four Times Each Day - 2 tab.
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