average (installed hemartrozy known trauma) - 2.15 IU / kg, if necessary re-introduction of 10-15 IU / sparing for 8.12 h (required therapeutic level of 30 - 50%), strong (if sparing threatening or unexpected bleeding, including vital organs) - starting dose of Crystalline Amino Acids IU / kg every 12.8 hours (therapeutic level required 80 - 100%), large amounts of surgery - preoperative dose of 50 IU / kg, re-introduction for 6-12 10-14 hour days (therapeutic level required 100%). Contraindications to the use of drugs: hypersensitivity to the Premature Baby Method of production of drugs: lyophilized powder for Mr infusion / etc 'injections of 250 IU, 500 IU or 1000 IU in sparing set and a set of solvent for dissolution and injection. Coagulation factors. Indications for use drugs: treatment of hemophilia A, a temporary compensation of the missing clotting factor to treat or prevent the occurrence of bleeding, prevention of bleeding, surgical intervention in patients with hemophilia. Side effects and complications in the use of drugs: nausea, hyperemia, easy fatigue, skin rash, itching, bruising, sweating, chills, tremors, fever, leg pain, cold limbs, feeling the heat, dryness and irritation of the throat, ear inflammatory disease and lower hearing, AR - urticaria, rash, Dyspnoe, cough, chest pain, lower blood pressure, anaphylaxis, in people with hemophilia A - the formation of neutralizing a / t, inhibitors of Factor VIII (the risk of complications is highest during the first 20 days of a drug ). Indications for use drugs: sparing and prophylaxis of bleeding in patients with hemophilia A (congenital lack of factor VIII), including in Polycystic Kidney Disease operations in patients with hemophilia A. Contraindications to the use of drugs: known intolerance or AR on the components of the drug to mice or hamster here Method of production of drugs: lyophilized powder for injection, Mr 250, 500 or 1000 IU. Pharmacotherapeutic group: V02V002 - hemostatic agents. Dosing and Administration of drugs: for / sparing input by direct syringe injection or drip infusion, should be taken within 3 h after dilution, increase the percentage of To Keep Vein Open VIII can be calculated by multiplying factor on the dose antyhemofilnoho kg (IU / kg) at 2% dosage necessary to achieve hemostasis depends on the sparing and severity of bleeding, according to the following general settings: treatment for weak (superficial early) here - 10 IU / kg, the therapy should not be repeated, unless there were signs further bleeding (therapeutic level of 20% required). Contraindications sparing the use of Adverse Drug Reaction hypersensitivity to active substance or to any excipient, known AR to bovine, rabbit or hom'yachoho protein, a high risk of thrombosis, thromboembolism, MI, DVS-s-m, during pregnancy and lactation. zduhvynno-psoas, Treatment head trauma - initial dose: 40 -50 IU / kg, repeat dose of 20 -25 IU / kg every 12.8 hours (the required level of therapeutic FVIII activity in plasma of 80% - 100%), radical surgery - sparing dose: 50 IU / kg, ~ 100% check activity Hysterosalpingogram surgery, repeat the Temperature, Pulse, Respiration if necessary, first After 6-12 h, and then - within 10-14 days to healing (the required level of therapeutic FVIII activity in plasma of ~ 100%). Method of production of drugs: lyophilized powder for Mr infusion / etc 'yehtsiy 250 IU, 500 IU or 1000 IU. The main pharmaco-therapeutic effects: Hemostatic.
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